Global Healthcare

Ketoconazole is a synthetic broad spectrum Anti-Fungal which is white to slightly beige, odorless powder, soluble in acids, with molecular wt.of 531.44 Mean peak plasma levels of approx.3.5mcg./ml are reached in 1,2 hours of oral administration. In Vitro Plasma Protein Binding is 99%. About 13% of dose is excreted in urine, the major route of excretion is through the bile into intestinal tract.